Matthias Berking*, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen, Germany David Daniel Ebert, Leuphana University Lueneburg, Lueneburg, Germany Claudia Buntrock, Leuphana University Lueneburg, Lueneburg, Germany Dirk Lehr*, Leuphana University Lueneburg, Lueneburg, Germany Heleen Riper, Free University Amsterdam, Amsterdam, Netherlands Pim Cuijpers, Free University of Amsterdam, Amsterdam, Netherlands Track: Research Presentation Topic: other Presentation Type: Poster presentation Submission Type: Single Presentation Last modified: 2014-05-15

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Background: Web-based interventions have shown to be effective in reducing depressive symptom severity. However, it is not known whether such interventions are also effective in preventing the onset of major depressive disorder (MDD) in at risk-populations. The aim of this study is to evaluate the effectiveness of an indicated web-based guided self-help intervention (GET.ON Mood Enhancer) on the onset of MDD in individuals with subthreshold depression.

Methods: In a randomized controlled trial, we compared the effectiveness of GET.ON Mood Enhancer with an online-based psychoeducation control condition (OPD) in adults with subthreshold depression (N=406). The primary outcome was time to onset of MDD within a 6-months follow-up period. Time to onset was assessed by telephone-administered structured clinical interviews.

Results: Work in progress. Findings will be presented on the conference.

Discussion: Work in progress. Findings will be discussed when presenting the findings.