Clinical Trials Using Mobile Health Applications



Melissa Ann LoPresti*, Neuro+Digital Initiative, Department of Neurosurgery, Columbia University Medical Center, New York, NY USA, New York, United States
Mickey Abraham, Neuro+Digital Initiative, Department of Neurosurgery, Columbia University Medical Center, New York, NY USA, New York, United States
Olivier Bruyère, Department of Public Health, Epidemiology and Health Economics, ULg, Liège, Belgium, Liege, Belgium
Justin Slomian, Department of Public Health, Epidemiology and Health Economics, ULg, Liège, Belgium, Liege, Belgium
Jean-Yves Reginster, Department of Public Health, Epidemiology and Health Economics, ULg, Liège, Belgium, Liege, Belgium
Geoff Appelboom, Neuro+Digital Initiative, Department of Neurosurgery, Columbia University Medical Center, New York, NY USA, New York, United States
E. Sander Connolly, Neuro+Digital Initiative, Department of Neurosurgery, Columbia University Medical Center, New York, NY USA, New York, United States


Track: Research
Presentation Topic: Mobile & Tablet Health Applications
Presentation Type: Poster presentation
Submission Type: Single Presentation

Last modified: 2014-05-16
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Abstract


Background: Mobile health (mHealth) is a growing sector of technology used in clinical practice. With the ubiquity of this technology in today's society, the promise it holds for use in medicine is vast.

Purpose: To conduct a systematic review examining the current research and clinical trials involving mobile health applications used by human participants worldwide.

Design: We searched the clinicaltrials.gov database for all original trials examining mobile health applications role and use internationally and in varying clinical settings.

Results: Fifty trials were included. Eighty-eight percent of included trials were initiated from 2012 to 2014, with only 20% of all included trials currently completed. The overwhelming majority of trials originated from the United States (57%) and western/European countries (29%). There was a broad distribution of the trials in regards to study focus and purpose, involving application in behavior change (25%), treatment adherence (8%), disease management (47%), and patient-reported outcomes (20%). Most included trials were performed in the setting of chronic diseases.

Conclusion: The use of mHealth is a growing field with broad implications and indications in clinical practice. This trend of increasing trials, studies, and pervasiveness of technology in health care is a more recent development. Evidence in support of this technology is unclear from the trials included in this study; however, the significance of mobile health applications, devices, and technology most assuredly have a role in chronic disease management and work to improve patient engagement.




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