Clinical Trials Using Mobile Health Applications
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Abstract
Background: Mobile health (mHealth) is a growing sector of technology used in clinical practice. With the ubiquity of this technology in today's society, the promise it holds for use in medicine is vast.
Purpose: To conduct a systematic review examining the current research and clinical trials involving mobile health applications used by human participants worldwide.
Design: We searched the clinicaltrials.gov database for all original trials examining mobile health applications role and use internationally and in varying clinical settings.
Results: Fifty trials were included. Eighty-eight percent of included trials were initiated from 2012 to 2014, with only 20% of all included trials currently completed. The overwhelming majority of trials originated from the United States (57%) and western/European countries (29%). There was a broad distribution of the trials in regards to study focus and purpose, involving application in behavior change (25%), treatment adherence (8%), disease management (47%), and patient-reported outcomes (20%). Most included trials were performed in the setting of chronic diseases.
Conclusion: The use of mHealth is a growing field with broad implications and indications in clinical practice. This trend of increasing trials, studies, and pervasiveness of technology in health care is a more recent development. Evidence in support of this technology is unclear from the trials included in this study; however, the significance of mobile health applications, devices, and technology most assuredly have a role in chronic disease management and work to improve patient engagement.
Purpose: To conduct a systematic review examining the current research and clinical trials involving mobile health applications used by human participants worldwide.
Design: We searched the clinicaltrials.gov database for all original trials examining mobile health applications role and use internationally and in varying clinical settings.
Results: Fifty trials were included. Eighty-eight percent of included trials were initiated from 2012 to 2014, with only 20% of all included trials currently completed. The overwhelming majority of trials originated from the United States (57%) and western/European countries (29%). There was a broad distribution of the trials in regards to study focus and purpose, involving application in behavior change (25%), treatment adherence (8%), disease management (47%), and patient-reported outcomes (20%). Most included trials were performed in the setting of chronic diseases.
Conclusion: The use of mHealth is a growing field with broad implications and indications in clinical practice. This trend of increasing trials, studies, and pervasiveness of technology in health care is a more recent development. Evidence in support of this technology is unclear from the trials included in this study; however, the significance of mobile health applications, devices, and technology most assuredly have a role in chronic disease management and work to improve patient engagement.
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